Nobivac EDGE DAPPv+L4 is a 0.5 mL combo vaccine that provides parainfluenze protection in combination with four-way leptospirosis protection.

• Aids in the prevention of disease, mortality, and leptospiriuria caused by four Leptospira serovars
• 0.5 mL combination vaccine formula to include parainfluenza
• Protects against all known strains of canine parvovirus (CPV), including CPV-2c
• Contains CPV-2b, one of the most prevalent field strains of parvovirus
• High antigenic mass (titer), low passage parvovirus vaccine
• Overrides CPV maternal antibodies in young puppies
• Systemic administration stimulates a strong IgG response (CPiV)
• Protects against adenovirus type 1 that causes hepatitis in dogs

Safety & Quality

• 99% Reaction Free: out of 1,583 doses given in Clinical Impressions study
• Lower total protein level than other 0.5 ml vaccine options
• Onderstepoort-type strain in Nobivac® vaccines provides a high level of safety (CDV)

• A porous filtration membrane selectively removes extraneous proteins, salts, and solvents
• Fewer total proteins (TP) means a more purified final product, which may reduce unwanted immune system responses such as vaccine reactions
• Promotes a higher level of vaccine quality
• Same process used for Nobivac® Lepto4, Nobivac®Canine-1 DAPPv+L4, and Nobivac EDGE™ Lepto4