Recommended for the vaccination of healthy dogs as an aid in the prevention of disease caused by canine distemper virus, adenovirus type 1 (hepatitis) and adenovirus type 2 (respiratory disease), canine parainfluenza virus, and canine parvovirus. Additionally, it is an aid in the prevention of disease, urinary shedding and mortality caused by L. canicola, L. icterohaemorrhagiae, L. pomona, or L. grippotyphosa.